Tissue factor based prothrombin time reagent

Details Tissue factor based prothrombin time reagent Tissue factor based prothrombin time reagent

C - Chemistry, Metallurgy

12

Q

C12Q 1/56 (2006.01) A61K 9/127 (2006.01) C07K 14/745 (2006.01) G01N 33/543 (2006.01) G01N 33/86 (2006.01)

Patent

CA 2096109

Prothrombin time reagents are provided which comprise novel liposome compositions in which tissue factor is associated with and inserted into the phospholipid bilayer of the liposomes. Methods for their preparation are also provided. The liposome compositions may be adjusted to allow maximum coagulant activity and sensitivity to extrinsic coagulation factors.

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