Tissue factor - kunitz domain fusion proteins as factor viia...

Details Tissue factor - kunitz domain fusion proteins as factor viia... Tissue factor - kunitz domain fusion proteins as factor viia...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/48 (2006.01) A61K 38/57 (2006.01) C07K 14/81 (2006.01) C12N 9/48 (2006.01) C12N 9/96 (2006.01) C12N 15/15 (2006.01) C12N 15/57 (2006.01)

Patent

CA 2237181

The invention provides compositions having a Factor VIIa active site inhibitor domain and a tissue factor domain for the inhibition of FVIIa. The invention also provides pharmaceutical compositions comprising the novel compositions as well as their use in diagnostic, therapeutic, and prophylactic methods.

L'invention concerne des compositions ayant un domaine inhibiteur de site actif du facteur VIIa et un domaine de facteur tissulaire pour l'inhibition du facteur FVIIa. On décrit par ailleurs des formulations pharmaceutiques comprenant les nouvelles compositions considérées, ainsi que leur utilisation à des fins diagnostiques, thérapeutiques et prophylactiques.

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