Tissue fusion method using collagenase for repair of soft...

A - Human Necessities – 61 – K

Patent

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A61K 38/48 (2006.01) A61K 47/30 (2006.01) A61B 17/56 (2006.01) A61F 2/30 (2006.01) A61K 35/74 (2006.01)

Patent

CA 2614162

The present invention provides a method of using locally administered collagenase as a non-invasive means of enhancing cell release from the cartilage or fibrocartilage tissues adjacent to a disease or injury site. The subsequent migration of cells from these tissues into the lesion or wound, followed by deposition of the appropriate extracellular matrix, results in closure of the lesion or fusion of a tissue gap.

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