Tissue glue prepared by using cryoprecipitate

Details Tissue glue prepared by using cryoprecipitate Tissue glue prepared by using cryoprecipitate

A - Human Necessities

61

K

A61K 35/14 (2006.01) A61L 2/00 (2006.01) A61L 24/00 (2006.01) A61L 24/10 (2006.01)

Patent

CA 2079077

A tissue glue is described comprising a component A which comprises a cryoprecipitate of whole blood and high an amount of a protease inhibitor corresponding to 3,000 to 5,000 KIU/ml units of aprotinin, and a component B comprising a proteolytic enzyme being capable of cleaving specifically fibrinogen present in component A and causing the formation of a fibrine polymer. In another embodiment an improved tissue glue is described comprising a component A which comprises a cryoprecipitate of whole blood, and a component B comprising a proteolytic enzyme obtainable from snake venom which enzyme is capable of cleaving specifically fibrinogen present in component A and causing the formation of a fibrine polymer.

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