Tissue-mimicking phantom for prostate cancer brachytherapy

G - Physics – 09 – B

Patent

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Details

G09B 23/28 (2006.01) A61M 36/06 (2006.01) A61N 5/10 (2006.01)

Patent

CA 2675217

A phantom for prostate cancer brachytherapy has a prostate tissue phantom shaped like a real prostate gland, a perineal tissue phantom surrounding the prostate tissue phantom, a skin tissue phantom separating the perineal tissue phantom from an outside environment, and an enclosure. The prostate tissue phantom is a polyvinyl alcohol cryogel (PVA-C) having undergone 3-5 freeze-thaw cycles and having 10- 20% w/w PVA in a solvent (e.g. water), 4-8% w/w oil and an amount of acoustic scattering particles to ultrasonically distinguish the prostate tissue phantom from its surroundings. The perineal tissue phantom is a PVA-C having undergone 1-2 freeze-thaw cycles and having 10-20% w/w PVA in a solvent, 4-8% w/w oil and an amount of acoustic scattering particles to ultrasonically distinguish the perineal tissue phantom from its surroundings. The skin tissue phantom is a PVA-C having undergone at least 6 freeze-thaw cycles and having 15-25% w/w PVA in a solvent. The phantom mimics the imaging and mechanical properties of the prostate and surrounding tissues, providing a realistic phantom for prostate cancer brachytherapy.

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