Tissue modeling in embryonic stem (es) cell system

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/0735 (2010.01) C12N 5/071 (2010.01) A61K 35/12 (2006.01) A61K 35/34 (2006.01) A61P 9/10 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2525847

Provided are embryonic stem (ES) cell-derived tissue modeling systems. In particular, systems for the de novo generation of tissue by parallel drug selection of cell types constituting the tissue of interest in one culture of differentiating ES cells is described as well as the use of such systems in transplantation and drug development.

L'invention concerne des systèmes de modélisation de tissu issu de cellules souches embryonnaires (ES). L'invention concerne notamment des systèmes de génération de novo de tissu par sélection médicamenteuse parallèle de types de cellules constituant le tissu à étudier dans une culture de cellules ES de différentiation ainsi que l'utilisation desdits systèmes dans la transplantation et le développement de médicaments.

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