Tissue plasminogen activator glycosylation variants with...

Details Tissue plasminogen activator glycosylation variants with... Tissue plasminogen activator glycosylation variants with...

C - Chemistry, Metallurgy

12

N

C12N 15/58 (2006.01) A61K 38/49 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12N 9/72 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2129660

The invention concerns tissue plasminogen activator (t-PA) variants which are glycosylated at any of positions 103-105, and are devoid of functional carbohydrate structure at position 117 of wild- type human t-PA amino acid sequence. The variants have extended circulatory half-life and substantially retained fibrin binding, or improved in vivo fibrinolytic potency, as compared to wild-type human t-PA.

Affiliated with

Also associated with

Rating

Tissue plasminogen activator glycosylation variants with... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tissue plasminogen activator glycosylation variants with..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tissue plasminogen activator glycosylation variants with... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1431184