Tissue repair compositions and methods for their manufacture...

A - Human Necessities – 61 – K

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A61K 35/32 (2006.01) A61L 27/28 (2006.01) A61L 27/34 (2006.01) A61L 27/36 (2006.01) A61L 27/56 (2006.01) C07K 1/14 (2006.01)

Patent

CA 2458959

An osteogenic composition is prepared by a process including the steps of subjecting demineralized bone to an extraction medium to produce an insoluble extraction product and a soluble extraction product, separating the insoluble extraction product and the soluble extraction product, drying the soluble extraction product to remove all or substantially all of the moisture in the soluble extraction product, and combining the dried soluble extraction product of step c) with demireralized bone particles. Preferably, the process does not involve heating.

Cette invention concerne une composition ostéogène préparée au moyen d'un procédé comprenant les étapes consistant : à soumettre un os déminéralisé à un agent d'extraction afin d'obtenir un produit d'extraction insoluble et un produit d'extraction soluble ; à séparer le produit d'extraction insoluble du produit d'extraction soluble ; à faire sécher le produit d'extraction soluble pour en extraire la totalité ou la quasi-totalité de l'humidité ; et à mélanger le produit d'extraction soluble séché obtenu dans la troisième étape avec des particules osseuses déminéralisées. L'échauffement n'intervient de préférence pas dans ce procédé.

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