Tissue sealant compositions and methods of use thereof

A - Human Necessities – 61 – L

Patent

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A61L 25/00 (1995.01)

Patent

CA 2247133

Novel tissue sealant compositions are disclosed herein which can be formulated as a single-component. The compositions contain as essential elements thromboplastin and fibrinogen. Additional blood clotting factors such as Factors II, V, VII, X, and XIII can also be added. Also provided are methods for promoting tissue adhesion and/or hemostatus by administering the tissue adhesive compositions described herein.

La présente invention concerne des compositions de fermeture tissulaire pouvant se formuler en un seul composant. Ces compositions contiennent, comme éléments essentiels, de la thromboplastine et du fibrinogène. Il es également possible d'ajouter à la composition des facteurs de coagulation sanguine tels que les Facteurs II, V, VII, X et XIII. L'invention concerne également des procédés favorisant l'adhésion tissulaire et/ou l'hémostase tissulaire par administration des compositions d'adhésion tissulaire de l'invention.

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