Tissue-specific imaging and therapeutic agents targeting...

Details Tissue-specific imaging and therapeutic agents targeting... Tissue-specific imaging and therapeutic agents targeting...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/00 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2572348

Methods of delivering an agent in a tissue-specific manner, particularly lung tissue, by targeting a protein expressed on the endothelial cell surface, are described. The methods can be used for detecting, imaging and/or treating pathologies, as well as for diagnostics.

La présente invention se rapporte à des procédés permettant d'administrer un agent en fonction du type de tissu, en particulier au tissu pulmonaire, par le ciblage d'une protéine exprimée sur la surface des cellules endothéliales. Les procédés selon l'invention peuvent servir à détecter, à imager et/ou à traiter des pathologies, ainsi qu'à des fins diagnostiques.

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