Titration package for neramexane and its use in the...

A - Human Necessities – 61 – K

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Details

A61K 31/13 (2006.01) A61J 1/03 (2006.01) A61J 7/00 (2006.01) A61K 9/28 (2006.01) A61P 27/16 (2006.01)

Patent

CA 2699210

The present invention relates to a titration scheme for the administration of a 1-amino-alkylcyclohexane derivative which allows for quick attainment of an effective dose of a 1-amino-alkylcyclohexane derivative while minimizing side effects. The present invention further relates to a titration package for providing a 1-amino-alkylcyclohexane derivative (e.g., neramexane or a pharmaceutically acceptable salt thereof) in at least two different dosages. The present titration scheme/titration package may be useful in the treatment of various diseases, including tinnitus.

La présente invention concerne un système de titrage pour l'administration d'un dérivé de 1-amino-alkylcyclohexane qui permet d'atteindre rapidement une dose efficace d'un dérivé de 1-amino-alkylcyclohexane tout en réduisant à un minimum les effets indésirables. La présente invention concerne en outre un ensemble de titrage destiné à fournir un dérivé de 1-amino-alkylcyclohexane (par ex., néramexane ou un sel pharmaceutiquement acceptable de celui-ci) en au moins deux doses différentes. Le système de titrage et l'ensemble de titrage de l'invention peuvent être utiles dans le traitement de diverses maladies, notamment de l'acouphène.

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