C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A01N 57/16 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 21/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2148368
2148368 9410301 PCTABS00032 This invention describes compounds active against TNF-.alpha. mRNA. It further describes RNA molecules capable of conferring stability to RNA in vivo through an endogenous ribozyme binding protein(s). Possible mRNA molecules to be stabilized include ribozymes, antisense molecules and mRNA encoding polypeptides useful for protein production. The ribozymes and antisense molecules described herein are useful in mammals and plants, particularly suited for viral diseases. Methods of production and methods of use are also described.
Gene Shears Pty. Limited
Gowling Lafleur Henderson Llp
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