C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/62 (2006.01) C07K 14/525 (2006.01) C12N 15/11 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01)
Patent
CA 2731388
The present invention refers to single-chain fusion proteins comprising three soluble TNF superfamily (TNFSF) cytokine domains and nucleic acid molecules encoding these fusion proteins. The fusion proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
La présente invention concerne des protéines de fusion à une seule chaîne comprenant les trois domaines de cytokine solubles de la superfamille des TNF (TNFSF) et des molécules d'acide nucléique codant ces protéines de fusion. Les protéines de fusion sont sensiblement non agrégeantes et appropriées à des applications thérapeutiques, diagnostiques et/ou de recherche.
Gieffers Christian
Hill Oliver
Thiemann Meinolf
Apogenix Gmbh
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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