Tocopherol-based pharmaceutical systems

Details Tocopherol-based pharmaceutical systems Tocopherol-based pharmaceutical systems

A - Human Necessities

61

K

167/163, 167/237

A61K 31/415 (2006.01) A61K 9/127 (2006.01)

Patent

CA 1333360

A method for making a pharmaceutical composition is described. The composition is comprised of an organic acid derivative of alpha tocopherol, and may additionally comprise other lipids. The composition may be in the form of liposomes, and as such are associated with or entrap a bioactive agent. Particularly suited for such systems are drugs stable at acidic pH, for example drugs having imidazole groups, such as pilocarpine. The composition requires a stabilizer to maintain the bilayer phase of the organic acid derivative of alpha tocopherol in a low pH environment. Such a stabilizer is for example a detergent. Upon in vivo administration of the system and concomitant increase of pH, viscosity of the preparation increases.

580562

Affiliated with

Also associated with

Rating

Tocopherol-based pharmaceutical systems does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tocopherol-based pharmaceutical systems, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tocopherol-based pharmaceutical systems will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1175874