Tocopherol compositions for delivery of biologically active...

A - Human Necessities – 61 – K

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A61K 47/22 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2189328

The present invention provides the use of a tocopherol or a derivative thereof as a solvent and/or emulsifier for substantially insoluble and sparingly soluble biologically active agents, especially in the manufacture of pharmaceutical compositions. Such compositions are particularly suitable for transmucosal, and especially intranasal or rectal administration, or administration via the oral cavity.

L'invention concerne l'utilisation d'un tocophérol ou d'un dérivé de celui-ci en tant que solvant et/ou émulsifiant destiné à des agents actifs biologiquement, sensiblement insolubles et difficilement solubles, notamment dans la fabrication de compositions pharmaceutiques. De telles compositions sont particulièrement appropriées pour être administrées aux muqueuses, notamment la muqueuse nasale ou rectale, ou pour être administrées par voie orale.

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