Tocopheryl ascorbyl phosphate-cyclodextrin clathrate and a...

Details Tocopheryl ascorbyl phosphate-cyclodextrin clathrate and a... Tocopheryl ascorbyl phosphate-cyclodextrin clathrate and a...

C - Chemistry, Metallurgy

08

B

C08B 37/16 (2006.01) A61K 8/67 (2006.01) A61K 8/73 (2006.01) A61K 31/715 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2213106

The invention provides a clathrate comprising a cyclodextrin or hydroxyalkylated cyclodextrin and, as included therein, dl-.alpha.-tocopheryl L-ascorbyl phosphate. In another aspect, the invention provides a dermal composition for external use, particularly a cosmetic composition. The composition is characterized by reduced foam production in aqueous solution and good stability against light.

L'invention présente un clathrate renfermant une cyclodextrine ou une cyclodextrine hydroxyalkylée et un phosphate de dl-alpha-tocophérol et de L-ascorbyle. Ou encore, l'invention propose une composition dermique pour usage externe, notamment une composition cosmétique. La composition est caractérisée par une production réduite de mousse en solution aqueuse et une bonne stabilité à la lumière.

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