Tolerizing and desensitizing compounds, compositions and...

C - Chemistry – Metallurgy – 07 – C

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260/490.2

C07C 69/035 (2006.01) A61K 39/35 (2006.01) A61K 47/48 (2006.01)

Patent

CA 1164473

TOLERIZING AND DESENSITIZING COMPOUNDS, COMPOSITIONS AND METHODS OF TREATMENT AGAINST DERMATOLOGICAL CONDITIONS CAUSED BY ALLERGENS FROM PLANTS AND TREES OF THE ANA- CARDIACEAE AND GINKGOACEAE FAMILIES ABSTRACT . Compounds, compositions and a method of treatment to tolerize and desensitize mammals sensitive to the allergenic moities found in plants of the Anacardiaceae and Ginkgoaceae families comprising the reaction product of poison ivy urushiol, poison oak urushiol, poison sumac urushiol & mixtures thereof, 3-n-alkane substituted catechol derivatives having 11 to 19 carbon atoms and the unsaturated olefinic congeners thereof with an acyl ester functioning group esterifying the catecholic hydroxy constituents of the aforementioned compounds or cell membrane residues.

335083

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