Tolerogenic dendritic cells, method for their production and...

A - Human Necessities – 61 – K

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A61K 35/12 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2652148

The present invention relates to a tolerogenic dendritic cell population (Tr-DC) capable of generating a population of T cells having regulatory activity, method of production and uses thereof. Furthermore, soluble HLA-G promotes the differentiation of a population of T cells with regulatory activity.

La présente invention concerne une population de cellules dendritiques tolérogènes (Tr-DC) permettant de générer une population de lymphocytes T présentant une activité régulatrice, un procédé pour leur production et leurs utilisations. En outre, le HLA-G soluble favorise la différenciation d'une population de lymphocytes T présentant une activité régulatrice.

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