Tolerogenic peptides from myelin basic protein

Details Tolerogenic peptides from myelin basic protein Tolerogenic peptides from myelin basic protein

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2473469

There is provided a peptide which is capable of binding to an MHC class I or II molecule without further processing (i.e. an apitope) which comprises a portion of the region (131-158) of myelin basic protein, in particular there is provided an apitope which is selected from the following myelin basic protein peptides: (134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140- 154). There is also provided the use of such a peptide in a pharmaceutical composition and a method to treat and/or prevent a disease using such a peptide.

L'invention concerne un peptide pouvant se lier à une molécule de complexe majeur d'histocompatibilité (MHC) de classe I ou II sans aucun autre traitement, tel qu'un apitope, comprenant une partie de la région 131-158 de la protéine basique de myéline. L'invention concerne en particulier un apitope sélectionné parmi les peptides de protéine basique de myéline suivants: 134-148, 135-149, 136-150, 137-151, 138-152, 139-153, 140-154. L'invention concerne également l'utilisation de ce peptide dans une composition pharmaceutique et un procédé de traitement et/ou de prévention d'une maladie au moyen de ce peptide.

Affiliated with

Also associated with

Rating

Tolerogenic peptides from myelin basic protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tolerogenic peptides from myelin basic protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tolerogenic peptides from myelin basic protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1564321