Tolperisone-containing pharmaceutical preparation for oral...

Details Tolperisone-containing pharmaceutical preparation for oral... Tolperisone-containing pharmaceutical preparation for oral...

A - Human Necessities

61

K

A61K 31/4453 (2006.01) A61J 3/10 (2006.01) A61K 9/20 (2006.01) A61K 9/28 (2006.01)

Patent

CA 2366841

The invention relates to a pharmaceutical preparation containing tolperisone or a salt thereof as an active ingredient in the form of a racemic mixture which can be a 50/50-racemate or a racemate with the preponderant content of the (-) isomer of tolperisone. The pharmaceutical preparation is formulated as a solid or liquid medicament for oral administration. The active ingredient tolperisone that is present as 50/50-racemate or as racemate with a preponderant content of the (-) isomer or the (+) isomer is liberated from the preparation in the human body in a delayed manner and preferably in the intestinal canal.

Composition pharmaceutique contenant comme principe actif de la tolpérisone ou un sel de tolpérisone, qui se présente sous forme de mélange racémique pouvant être un racémique 50/50 ou un racémique renfermant un plus fort pourcentage de l'isomère (-) de tolpérisone. Cette préparation pharmaceutique destinée à l'administration orale est formulée sous forme de médicament solide ou liquide pouvant être administré per os. La tolpérisone, principe actif pouvant se présenter sous la forme d'un racémique 50/50 ou d'un racémique contenant un plus fort pourcentage de l'isomère (-) ou de l'isomère (+), est libérée de la préparation et passe dans l'organisme humain de manière retardée, de préférence au niveau de l'intestin.

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