Tolterodine salts

A - Human Necessities – 61 – K

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Details

A61K 31/137 (2006.01) A61K 31/185 (2006.01) A61P 11/00 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2483092

The present invention concerns novel pharmaceutically active compounds, pharmaceutical compositions containing the same, the compounds for use as medicaments, and use of the compounds for the manufacture of specific medicaments. The present invention also concerns a method of treatment involving administration of the compounds. Specifically, the compounds are pharmaceutically acceptable salts of tolterodine or hydroxytolterodine, wherein the salt is of an acid selected from the group consisting of aliphatic mono- and dicarboxylic acids comprising from 7 to 24 carbon atoms, alkanedisulfonic acids comprising from 2 to 4 carbon atoms, naphthoic acid derivatives comprising from 11 to 27 carbon atoms, maleic acid and fumaric acid.

La présente invention concerne de nouveaux composés considérés comme principes actifs pharmaceutiques, des compositions pharmaceutiques à base de ces composés, les composés convenant comme médicaments, et l'utilisation de ces composés pour la fabrication de médicaments spécifiques. L'invention concerne également un traitement par lequel on administre ces composés. Ces composés sont des sels pharmaceutiquement admis de toltérodine ou d'hydroxytoltérodine, en l'occurrence, un sel d'un acide du groupe constitué des acides mono et dicarboxyliques aliphatiques en C¿7?-C¿24?, acides alcanedisulfoniques en C¿2?-C¿4?, dérivés d'acide naphtoïque en C¿11?-C¿24?, acide maléique, et acide fumarique.

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