Topical administration of certain azaspiranes to prevent or...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/695 (2006.01) A61K 9/70 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/403 (2006.01) A61K 31/438 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2257875

A locally administrable topical pharmaceutical composition is provided for prevention or treatment of skin conditions associated with hyperproliferation of skin cells and/or an immunologically mediated disorder, e. g., psoriasis, atopical dermatitis, contact dermatitis, seborrhoeic dermatitis, lupus and the like. The composition contains a topical carrier and spirogermanium or a structurally related azaspirane. Also provided are methods for using the novel composition and laminated patches which may be applied to the skin to administer the composition thereto.

La présente invention concerne une composition pharmaceutique à administration locale pour la prévention ou le traitement des syndromes cutanés associés au phénomène d'hyperprolifération des cellules cutanées et/ou à des désordres immunologiquement contagieux, tels le psoriasis, l'eczéma constitutionnel, la dermite de contact, l'eczéma séborrhéïque, le lupus érythémateux et autres maladies similaires. La composition contient un excipient local au spirogermanium ou un azaspirane structurellement apparenté. L'invention a aussi recours à des procédés d'utilisation des nouvelles compositions et de supports stratifiés à appliquer sur la peau pour administrer ladite composition.

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