Topical anti-inflammatory drug therapy

A - Human Necessities – 61 – K

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167/159, 167/196

A61K 31/38 (2006.01) A61K 31/56 (2006.01) A61K 31/57 (2006.01) A61K 31/58 (2006.01) A61K 31/60 (2006.01) A61K 47/10 (2006.01) A61K 47/20 (2006.01)

Patent

CA 1101334

ABSTRACT OF THE DISCLOSURE A pharmaceutical composition for topical treatment of cutameous disorders or disruptions characterized by skin inflammation or hyperproliferative epidermal activity comprises the combination of a topically active anti-inflammatory corticosteroid and a non-steroidal anti-inflammatory agent which is an inhibitor of prostaglandin synthetase selected from the group consisting of the hydratropic acid derivations; acetylsalicylic acid; the pyrazolonedericativen; the fenamic acid derivatives; the aroyl-substituted pyrroles and the substituted arylacetohydroxamic acids in a pharmaceutically acceptiable topical vehicle. Treatment of above cutaneous disorders may also be effected by concurrent therapy using separate applications of corticosteriod and non-steroid.

277688

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