Topical co-enzyme q10 formulations and methods of use

Details Topical co-enzyme q10 formulations and methods of use Topical co-enzyme q10 formulations and methods of use

A - Human Necessities

61

K

A61K 31/122 (2006.01) A61K 8/35 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2553690

Topical formulations of CoQ10 reduce the rate of tumor growth in an animal subject. In the experiments described herein, CoQ10 was shown to increase the rate of apoptosis in a culture of skin cancer cells but not normal cells. Moreover, treatment of tumor-bearing animals with a topical formulation of CoQ10 was shown to dramatically reduce the rate of tumor growth in the animals.

La présente invention a trait à des formulations topiques de coenzyme Q10 réduisant le taux de croissance tumorale chez un animal sujet. Dans des expériences décrites dans l'invention, il a été démontré que la coenzyme Q10 accroît le taux d'apoptose dans une culture de cellules cancéreuses de la peau mais pas des cellules normales. En outre, il a été démontré que le traitement d'animaux portant des tumeurs avec une formulation topique de la coenzyme Q10 réduit de manière dramatique le taux de la croissance tumorale chez les animaux.

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