Topical composition comprising a cyclic imidocarbonate-based...

A - Human Necessities – 61 – K

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Details

A61K 8/49 (2006.01) A61Q 1/00 (2006.01) A61Q 1/06 (2006.01) A61Q 15/00 (2006.01) A61Q 17/04 (2006.01)

Patent

CA 2448240

The present invention relates to cosmetic compositions that comprise: a) a safe and effective amount of a cyclic imidocarbonate bonding agent having the structure (I) wherein X represents a cosmetic benefit agent that may or may not be attached via a chemical linker and R represents NH or O; and b) a cosmetically acceptable carrier for the bonding agent wherein the composition is administered topically to mammalian proteinaceous substrates and wherein the bonding agent reacts with a protein contained in the substrate such that the bonding agent, and thus the cosmetic benefit agent, is covalently attached to the substrate. The invention further relates to methods of using the compositions described above as well as various products that include the claimed compositions.

L'invention concerne des compositions pharmaceutiques renfermant: a) une quantité sûre et efficace d'un agent de liaison à base d'imidocarbonate cyclique de structure (I) dans laquelle X représente un agent cosmétique esthétique pouvant ou ne pouvant pas être fixé à un agent de liaison chimique et R représente NH ou O; et b) un excipient acceptable sur le plan cosmétique destiné à l'agent de liaison, la composition étant administrée de manière topique à des substrats protéiques mammifères et l'agent de liaison réagissant avec une protéine renfermée dans le substrat, de manière que l'agent de liaison et, par conséquent, l'agent cosmétique esthétique, soient fixés par covalence au substrat. L'invention concerne également des procédés d'utilisation des compositions selon l'invention, ainsi que divers produits renfermant lesdites compositions.

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