Topical composition containing human epidermal growth factor

Details Topical composition containing human epidermal growth factor Topical composition containing human epidermal growth factor

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 31/75 (2006.01)

Patent

CA 2321829

The present invention relates to a topical composition containing human epidermal growth factor (hEGF). More specifically, the present invention relates to a topical composition prepared by using polyoxyethylene- polyoxypropylene copolymer (Generic name: Poloxamer) having a viscosity of 4- 10 cps at 37 ~C, 60 rpm as the base for topical formulation to improve the wound healing ability of hEGF. The topical composition according to the present invention can sufficiently exhibit the wound healing effect of hEGF and therefore is useful for the treatment of cutaneous injuries including wounds, incisions, burns, etc.

La présente invention se rapporte à une composition topique contenant un facteur de croissance épidermique d'origine humaine (hEGF). De manière plus spécifique, cette invention se rapporte à une composition topique préparée à partir d'un copolymère polyoxyéthylène-polyoxypropylène (nom générique : Poloxamère) doté d'une viscosité comprise entre 4 et 10 cps, mesurée à 37 ·C et à 60 tours/minute, et utilisé comme base pour la formulation topique de façon à accroître le potentiel de cicatrisation du facteur hEGF. Ladite composition topique peut ainsi être dotée de manière suffisante du potentiel de cicatrisation du facteur hEGF et de ce fait, elle s'avère utile pour le traitement des blessures cutanées et notamment des plaies, des incisions, des brûlures, etc.

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