Topical compositions

Details Topical compositions Topical compositions

A - Human Necessities

61

K

A61K 9/107 (2006.01) A61K 31/215 (2006.01) A61K 31/425 (2006.01) A61K 31/465 (2006.01) A61K 31/54 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2289966

The invention concerns a topical composition comprising an emulsion of at least one discontinuous phase in a continuous phase, the or each discontinuous phase including a eutectic mixture of first and second pharmacologically active agents and the continuous phase being provided by a pharmaceutically acceptable carrier, the eutectic mixture having a melting point below 40 ~C. The topical composition may additionally comprise, in the eutectic mixture, a third or fourth pharmaceutically acceptable component.

Cette invention concerne une composition topique qui comprend une émulsion d'une ou de plusieurs phases discontinues dans une phase continue, les phases discontinues contenant chacune un mélange eutectique. Ce mélange comprend un premier et un deuxième agents pharmaceutiques actifs, tandis que la phase continue consiste en un excipient acceptable sur le plan pharmaceutique. Le mélange eutectique possède une température de fusion inférieure à 40 ·C. La composition topique peut en outre comprendre, dans le mélange eutectique, un troisième ou un quatrième composants acceptables sur le plan pharmaceutique.

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