Topical compositions and methods for treating pain

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/107 (2006.01) A61F 13/00 (2006.01) A61K 45/06 (2006.01) A61K 47/00 (2006.01) A61K 47/10 (2006.01) A61K 47/06 (2006.01) A61K 47/14 (2006.01) A61K 47/24 (2006.01) A61K 47/26 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2457780

Topical compositions and methods for treating pain. The invention provides oil- in-water emulsions comprising an antidepressant; an NMDA-receptor antagonists; a lipophilic component; water; and a surfactant. The compositions induce a local-anesthetic effect when topically administered to intact skin thereby treating or preventing pain, for example, neuropathic pain.

La présente invention concerne des compositions topiques et des méthodes de traitement de la douleur. Cette invention concerne des émulsions de type aqueux comprenant un antidépresseur; un antagoniste du NMDA; un composant lipophile; de l'eau; et un tensioactif. Ces compositions ont un effet anesthésique local lorsqu'elles sont administrées par application topique sur une peau intacte, ce qui permet de traiter ou d'empêcher la douleur, par exemple, la douleur neuropathique.

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