Topical compositions containing phosphorylated polyphenols

A - Human Necessities – 61 – K

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A61K 31/66 (2006.01)

Patent

CA 2579784

The present invention provides topical compositions containing phosphorylated polyphenols in combination with a topically acceptable carrier. The compositions of the invention provide a means for delayed delivery of the polyphenol to keratinous tissues, such as skin, hair and nails, with enzymes of the keratinous tissue dephosphorylating the polyphenol, and returning it to its native active form. The compositions are particularly useful in the regulation of skin conditions.

La présente invention concerne des compositions topiques contenant des polyphénols phosphorylés combinés à un excipient acceptable topiquement. Les compositions de cette invention engendrent un moyen d'administration retardée du polyphénol aux tissus kératineux, tels que la peau, les cheveux et les ongles, des enzymes du tissu kératineux déphosphorylant le polyphénol et le retournant à sa forme active d'origine. Ces compositions sont, particulièrement, utilisées dans la régulation de troubles cutanés.

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