Topical formulations for treatment of neuropathy

Details Topical formulations for treatment of neuropathy Topical formulations for treatment of neuropathy

A - Human Necessities

61

K

A61K 31/196 (2006.01) A61K 31/137 (2006.01) A61P 25/02 (2006.01)

Patent

CA 2738468

Topical treatments for neuropathy are described. The treatments include topical formulations of NMDA antagonists and one additional active ingredient. In one example, the formulation includes ketamine and gabapentin for the treatment of a subject's neuropathy. These transdermal or topical compositions provide a surprising degree of effective relief from the symptoms of peripheral neuropathy and can be administered to subjects to treat various neuropathies.

La présente invention concerne des traitements topiques pour une neuropathie. Les traitements comprennent des formulations topiques dantagonistes de NMDA et une substance active additionnelle. Dans un exemple, la formulation comprend de la kétamine et de la gabapentine pour le traitement dune neuropathie chez un sujet. Ces compositions transdermiques ou topiques présentent un degré inattendu datténuation effective des symptômes de neuropathie périphérique et peuvent être administrées à des sujets pour traiter différentes neuropathies.

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