Topical gel matrix

A - Human Necessities – 61 – L

Patent

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Details

A61L 26/00 (2006.01) A61D 7/00 (2006.01) A61K 9/70 (2006.01) A61K 47/34 (2006.01) A61L 15/26 (2006.01) A61L 15/44 (2006.01) A61K 7/40 (2000.01) A61K 35/78 (2000.01)

Patent

CA 2444781

This invention relates to a topical gel matrix that can be used alone or combination with a medication entrapped therein. The gel matrix is slowly dispersible in water so that it resists water degradation or disintegration for a substantial amount of time. The contact time with the skin, mucus or mucosa of a treated subject is long enough to allow slow diffusion of a medication entrapped therein. When used alone, the gel matrix provides a physical barrier against the penetration of a pathogen or environmental constituents into the wound, or conversely, contamination from the wound to the environment. It further eliminates or reduces the sensation of burn or irritation when applied on a scratch, injured or wounded skin or mucosa. The get may have the following generic composition: oil, water or aqueous solution; solvents, surfactants and/or detergents; and a polymer which is a consistence modifier capable of thickening and to resist degradation in a water environment. Aculyn 44TM is a preferred example of such a polymer. The matrix may comprise or not a biologically active ingredient. The ingredient is for a systemic or topical indication. Amongst preferred medications are anaesthetic, anti- histaminic, anti-inflammatory, anti-oxidant, anti-UVs, anti-microbial and wound healing agents. More specifically, for the treatment of fish infections, examples of preferred active ingredients are natural or synthetic plant extracts (Sweet Birch, pine, coriander, and clove oils).

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