A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/192 (2006.01) A61K 9/06 (2006.01) A61K 47/32 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2599968
Topical alcoholic gel compositions are disclosed that are useful for delivering therapeutic levels of an NSAID to target in and below the skin. The compositions comprise a topically active drug, an alcoholic solvent, a polymeric thickener, and optionally a keratolytic agent. In one embodiment, excellent viscosity for dermal application is attained without the need of a step for neutralizing the pH of the composition. Alcoholic and alcohol-free topical compositions comprising an NSAID prodrug are also disclosed. The compositions are particularly useful for the treatment of pseudo folliculitis barbae.
L~invention concerne des compositions de gels topiques alcooliques permettant de libérer des doses thérapeutiques d~un AINS de manière ciblée dans et sous la peau. Les compositions comprennent un médicament actif topiquement, un solvant alcoolique, un épaississant polymérique, et éventuellement un agent kératolytique. Selon un mode de réalisation, on obtient une viscosité excellente pour application dermique sans qu~une étape de neutralisation du pH de la composition ne soit nécessaire. L~invention concerne également des compositions topiques alcooliques et sans alcool, comprenant un promédicament AINS. Les compositions sont particulièrement utiles pour traiter le Pseudofolliculitis Barbae.
Spann-Wade Monique
Ward Anthony J.
Isw Group Inc.
Macpherson Leslie & Tyerman Llp
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