Topical herbal formulation for treatment of acne and skin...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/107 (2006.01) A61K 31/194 (2006.01)

Patent

CA 2746566

The present invention provides novel herbal nano emulsion based formulations comprising a combination of lemon juice and /or rose water as therapeutically active aqueous phase entrapped in oil phase selected from one or more essential oils and process for the preparation of the same in pharmaceutically acceptable dosage forms for topical treatment of acne and other skin disorder like eczema, psoriasis, aging scaring and the like with increased efficacy, Improved percutaneous penetration, excellent thermodynamic stability ensuring long shelf life, low skin irritation and reservoir effect that promotes drug localization in the skin enabling controlled delivery of the said therapeutic agents.

La présente invention concerne des formules basées sur une nouvelle nano-émulsion phytosanitaire comprenant une combinaison de jus de citron et/ou d'eau de rose au titre de phase aqueuse thérapeutiquement active, piégée dans une phase huileuse choisie parmi une ou plusieurs huiles essentielles, ainsi qu'un procédé d'élaboration desdites formules en formes galéniques de qualité pharmaceutique pour le traitement topique de l'acné et d'autres troubles cutanés comme l'eczéma, le psoriasis, le vieillissement, les cicatrices, etc. avec une efficacité améliorée, une pénétration percutanée amplifiée, une excellente stabilité thermodynamique garantissant une importante durée de vie en pot, une faible irritation cutanée et un effet de réservoir favorisant la localisation du médicament sur la peau et permettant la libération contrôlée desdits agents thérapeutiques.

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