Topical l-carnitine compositions

Details Topical l-carnitine compositions Topical l-carnitine compositions

A - Human Necessities

61

K

A61K 8/44 (2006.01) A61K 8/36 (2006.01) A61K 8/66 (2006.01) A61Q 19/00 (2006.01)

Patent

CA 2519998

The present invention is a topical composition comprising (a) L~carnitine, an acyl L-carnitine, a salt thereof, or a mixture thereof and (b) one or more hydroxy acids, proteolytic enzymes, skin lightening agents, or a mixture thereof, in a pharmacologically acceptable vehicle for topical application. The topical composition may be administered to improve or prevent deleterious skin conditions (e.g., epidermal exfoliation and loss of skin elasticity), exfoliate skin, accelerate skin turnover, and/or lighten skin. For example, it can be administered to minimize scar formation due to varicella infection, drying and peeling due to sunburn, and to improve skin elasticity. The topical composition preferably has a pH ranging from about 3.5 to about 8. According to one embodiment, the pH of the topical composition ranges from about 3.5 to about 6.5 or 7. According to another embodiment, the pH of the topical composition ranges from about 6 to about 8 and preferably from about 6.5 to 7.5. According to one preferred embodiment, the topical composition is preferably substantially free of D-carnitine, acyl D-carnitine, and salts thereof and, more preferably, is further substantially free of LD-carnitine, acyl LD-carnitine, and salts thereof.

L'invention concerne une composition topique renfermant (a) de la L-carnitine, une acyle L-carnitine, un sel correspondant, ou un mélange correspondant et (b) un(e) ou plusieurs hydroxy acides, enzymes protéolytiques, agents d'éclaircissement de la peau, ou un mélange correspondant, dans un véhicule pharmaceutiquement acceptable, aux fins d'application topique. On peut administrer cette composition pour améliorer ou prévenir des états délétères de la peau (par exemple, exfoliation de l'épiderme et perte d'élasticité de la peau), exfolier la peau, accélérer le remplacement de la peau, et/ou éclaircir la peau, par exemple pour réduire au minimum la formation de cicatrices suite à la varicelle, l'assèchement et le pelage suite à un coup de soleil, et améliorer l'élasticité de la peau. De préférence, le pH est compris entre environ 3,5 et environ 8. Selon une variante, le pH est compris entre environ 3,5 et environ 6,5 ou 7. Selon une autre variante, le pH est compris entre environ 6 et environ 8 et de préférence entre environ 6,5 et 7,5. En mode de réalisation préféré, la composition est sensiblement dépourvue de D-carnitine, d'acyle D-carnitine, et de sels correspondants, et de préférence encore, sensiblement dépourvue de LD-carnitine, d'acyle LD-carnitine, et des sels correspondants.

Affiliated with

Also associated with

Rating

Topical l-carnitine compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Topical l-carnitine compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topical l-carnitine compositions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1633180