Topical non-steroidal anti-inflammatory drug composition

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/19 (2006.01) A61K 9/70 (2006.01) A61K 31/192 (2006.01) A61K 31/195 (2006.01) A61K 31/54 (2006.01) A61K 47/12 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2304191

A means and method for treating inflamed mucosal tissues topically with a non- steroidal anti-inflammatory drug (NSAID) is described. The NSAID is incorporated into a substantive film forming aqueous based carrier system consisting of a water dispersible natural cellulosic polymer and an organic acid. The NSAID composition may further include a water soluble or water hydratable viscosity enhancing agent and/or a plasticizer. The NSAID topical composition is especially effective in treating pain associated with vulvodynia or vulvar vestibulitis.

La présente invention concerne un moyen et un procédé permettant le traitement topique des tissus muqueux avec un anti-inflammatoire non-stéroïdien. Cet anti-inflammatoire non-stéroïdien est incorporé à la substance d'un système vecteur filmogène à base aqueuse constitué d'un polymère cellulosique naturel hydrodispersable et d'un acide organique. Cette composition d'anti-inflammatoire non-stéroïdien comporte en outre un renforçateur de viscosité et/ou un émollient hydrosoluble ou hydratable à l'eau. Cette composition d'anti-inflammatoire non-stéroïdien topique contient particulièrement au traitement des douleurs associées à la vulvodynie ou à la vestibulite vulvaire.

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