Topical ophthalmic suspensions

A - Human Necessities – 61 – K

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A61K 9/06 (2006.01) A61K 9/00 (2006.01) A61K 47/30 (2006.01)

Patent

CA 2086120

Lightly cross-linked polymer, of which at least about 60 % by weight of the polymer, has been prepared by suspension or emulsion polymerizing at least about 50 % by weight of a carboxyl-containing monoethylenically unsaturated monomer acrylic acid with from about 0.1 % to about 5 % by weight of a non-polyalkenyl polyether difunctional cross-linking agent having a dry particle size of not more than about 30 µm in equivalent spherical diameter are formulated with water and at least one ophthal- mic demulcent; or at least one ophthalmic demulcent and at least one ophthalmic vasoconstrictor, into aqueous suspensions in which the amount of polymer ranges from about 0.1 % to about 6.5 % by weight.

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