Topical pharmaceutical composition comprising a cholinergic...

Details Topical pharmaceutical composition comprising a cholinergic... Topical pharmaceutical composition comprising a cholinergic...

A - Human Necessities

61

K

A61K 31/4422 (2006.01) A61K 31/167 (2006.01) A61P 9/14 (2006.01) A61K 31/455 (2006.01)

Patent

CA 2554085

A cholinergic agent and/or a calcium channel blocker is administered locally to the anus for the treatment of benign anal disorders, in particular anal fissures and haemorrhoids. The agents induce a reduction in the mean and resting pressure, thereby assisting in the healing of the anal fissures and haemorrhoids. Particularly preferred active agents are bethanechol and diltiazem, more particularly a combination thereof.

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