Topical pharmaceutical formulation

Details Topical pharmaceutical formulation Topical pharmaceutical formulation

A - Human Necessities

61

K

A61K 9/00 (2006.01)

Patent

CA 2680074

A composition for topical application of an NSAID comprises a solution or suspension of the NSAID in a carrier system comprising a polyhydric alcohol, a glycol ether and an ester of A higher fatty acid, the carrier system being present as a single phase at ambient temperatures. The NSATD may be diclofenac as diclofenac acid. The polyhydric alcohol may be a glycol such as isopropylene glycol and the glycol ether may be a diethylene glycol ether such as diethylene glycol monoethyl ether.

La présente invention concerne une composition pour application topique d'un AINS comprenant une solution ou une suspension dudit AINS dans un système porteur contenant un alcool polyhydrique, un éther de glycol et un ester d'acide gras supérieur. Ledit système porteur est présent sous forme d'une phase unique à des températures ambiantes. L'AINS peut être du diclofénac sous forme d'acide de diclofénac. L'alcool polyhydrique peut être un glycol, tel qu'un glycol d'isopropylène, et l'éther de glycol peut être un éther de glycol de diéthylène, tel que le diéthylène glycol monoéthyl éther.

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