Topical preparations containing cyclosporin

Details Topical preparations containing cyclosporin Topical preparations containing cyclosporin

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 9/06 (2006.01) A61K 47/00 (2006.01) A61K 47/02 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/18 (2006.01) A61K 47/44 (2006.01)

Patent

CA 2090417

38 ABSTRACT OF THE DISCLOSURE Disclosed is a topical preparation containing cyclosporin as an active ingredient, which contains (a) cyclosporin, (b) an organic solvent for dissolving said cyclosporin; (c) an ester of a fatty acid with a monovalent alcohol having a total number of carbon atoms of 8 or more and/or an alkanol amine, each being in liquid state at 25°C; (d) an oily substance in solid state at 25° C; and (e) a surfactant; wherein said cyclosporin is contained at a rate ranging from approximately 0.1% to 10% by weight and said ester and/or said alkanol amine are/is contained at a rate ranging from approximately 1% to 15% by weight. The topical preparations are active against atopic dermatitis, psoriasis, allergic contact dermatitis.

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