Topical regulation of triglyceride metabolism

C - Chemistry – Metallurgy – 12 – P

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C12P 7/64 (2006.01) A61K 6/00 (2006.01)

Patent

CA 2564319

The present invention relates to methods of topically applying compositions useful in enhancing triglyceride concentration in the lipid barrier of the skin comprising an effective amount of palmitoleic acid, or derivatives thereof, as the sole fatty acid component in combination with a pharmaceutically or cosmetically acceptable carrier. Such compositions are useful in the treatment or prevention of dry skin and conditions in which the skin's lipid barrier is defective or damaged.

L'invention concerne des méthodes d'application topique de compositions destinées à renforcer la concentration de triglycérides dans la barrière lipidique de la peau. Ces compositions contiennent une quantité efficace d'acide palmitoléique, ou de dérivés de celui-ci, comme unique composant acide gras, associé à un excipient pharmaceutiquement ou cosmétiquement acceptable. Ces compositions sont utiles dans le traitement ou la prévention de la sécheresse cutanée et des états caractérisés par une barrière lipidique cutanée défectueuse ou endommagée.

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