Topical stabilized prostaglandin e compound dosage forms

Details Topical stabilized prostaglandin e compound dosage forms Topical stabilized prostaglandin e compound dosage forms

A - Human Necessities

61

K

A61K 31/5575 (2006.01) A61K 9/00 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2512015

Compounds of prostaglandin E group (PGE compounds) are stabilized as non- aqueous compositions that include the compound together with a bulking agent that can be a non-aqueous liquid or a solid in a sheet, film or powder form. The composition can optionally include a skin penetration enhancer. A non- aqueous, solid dosage form comprises a PGE compound substantially uniformly distributed in a carrier sheet or film.

L'invention porte sur des composés de prostaglandine du groupe E (PGE) stabilisés, sous forme de compositions non aqueuse associées à un agent gonflant pouvant être un liquide non aqueux ou un solide en feuille, en film ou en poudre, et facultativement à un renforçateur de pénétration dermique. L'invention porte également sur une forme posologique solide non aqueuse comprenant un tel composé de PGE réparti quasi uniformément dans une feuille ou un film support.

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