Topical steroidal formulations

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/566 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 19/02 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2729343

The present invention relates to formulations of poorly water soluble pharmaceutical agents of Formula I and II. The present invention also relates to compositions containing compounds of Formula I or II, and glucocorticoids, and methods for reducing side effects from glucocorticoid treatment by co-administration of compounds of Formula I and II. The compositions herein are useful for the treatment of diabetes and obesity related diseases including metabolic syndrome.

La présente invention concerne des formulations dagents pharmaceutiques peu solubles dans leau de formule I et II. La présente invention concerne en outre des compositions contenant des composés de formule I ou II, et des glucocorticoïdes, et des procédés pour réduire les effets secondaires dun traitement avec des glucocorticoïdes par co-administration de composés de formule I et II. Les présentes compositions sont utiles pour le traitement du diabète et des maladies associées à lobésité, notamment le syndrome métabolique.

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