Topically active ocular gem-diacylthiadiazole sulfonamide...

Details Topically active ocular gem-diacylthiadiazole sulfonamide... Topically active ocular gem-diacylthiadiazole sulfonamide...

C - Chemistry, Metallurgy

07

D

C07D 285/135 (2006.01) A61K 31/425 (2006.01)

Patent

CA 2077995

2077995 9114683 PCTABS00007 This invention relates to compounds of formula (I) useful as a carbonic anhydrase inhibitor. A compound of formula (I) and pharmaceutically acceptable salts thereof, wherein X is NR12; R1 is (II); R2 is (III); R3 is hydrogen or lower alkyl; R is hydrogen or lower alkyl; each R4 and R5 are independently hydrogen or lower alkyl; each R7 and R8 are independently hydrogen or lower alkyl; R6 is OR10 or NR10R11; R9 is OR13 or NR11R13; R10, R11, R12, and R13 are independently hydrogen or lower alkyl; and n and m are independently 0-6.

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