A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/179
A61K 31/66 (2006.01) A61K 9/06 (2006.01) A61K 9/70 (2006.01) A61K 31/675 (2006.01)
Patent
CA 2020557
4-17658/+ Topically administrable pharmaceutical preparations Abstract The invention relates to topically administrable pharmaceutical preparations containing pharmaceudcally acceptable methanediphosphonic acid derivatives of formula Image (I) and their salts, wherein each of R1 and R2 is halogen, or wherein Rl is hydrogen and R2 is Ar-S- or Het1-NH-, in which Ar is unsubstituted or substituted phenyl and Het1 is unsubsdtuted or substituted, monocyclic, 5- or 6-membered monoaza-, diaza- or thiaza-aryl that is bonded via a ring carbon atom, or wherein R1 is hydrogen or hydroxy and R2 is -A-R3, in which A is alkylene and, on the one hand, R3 is Het2, which is Hetl bonded via a ring carbon or ring nitrogen atom, or, on the other hand, R3 is hydrogen, or amino that is unsubstituted or mono- or di-substituted by idendcal or different substituents selected from alkyl, cycloalkyl, Ar-alkyl, Ar-O-alkyl, Ar-S-alkyl and Hetl-alkyl, or that is disubstituted by optionally Ar-containing alkylene, wherein two alkylene carbon atoms may additionally be linked to one another via alkylene and Ar and Hetl are each as defined above, with the proviso that when R2 is -A-R3, A is ethylene and R3 is unsub- stituted or C1-C3alkyl-substituted amino, R1 is other than hydroxy.
Ferrini Pier Giorgio
Green Jonathan
Stahl Peter Heinrich
Voellmy Carlo
Fetherstonhaugh & Co.
Novartis Ag
LandOfFree
Topically administrable pharmaceutical preparations does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Topically administrable pharmaceutical preparations, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Topically administrable pharmaceutical preparations will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1422668