Total synthesis of salinosporamide a and analogs thereof

Details Total synthesis of salinosporamide a and analogs thereof Total synthesis of salinosporamide a and analogs thereof

C - Chemistry, Metallurgy

07

D

C07D 207/26 (2006.01) C07D 263/04 (2006.01) C07D 491/04 (2006.01) C07D 498/04 (2006.01) C07D 498/14 (2006.01)

Patent

CA 2648317

The present invention relates to certain compounds and to methods for the preparation of certain compounds that can be used in the fields of chemistry and medicine. Specifically, described herein are methods for the preparation of various compounds and intermediates, and the compounds and intermediates themselves. More specifically, described herein are methods for synthesizing Salinosporamide A and its analogs from a compound of formula (V).

L'invention concerne certains composés et des méthodes pour la préparation de certains composés qui peuvent être utilisés dans les domaines de la chimie et de la médecine. D'une manière plus spécifique, l'invention concerne des méthodes pour la préparation de divers composés et intermédiaires ainsi que ces composés et ces intermédiaires eux-mêmes. D'une manière plus spécifique, l'invention concerne des méthodes permettant de synthétiser la Salinosporamide A et ses analogues à partir d'un composé représenté par la formule (V).

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