Toxicological response markers

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2340589

The present invention relates to a composition comprising a plurality of nucleic acid molecules. The composition can be used as hybridizable array elements in a microarray. The present invention also relates to methods for screening compounds and therapeutics for metabolic responses indicative of a toxic compound.

L'invention concerne une composition comprenant plusieurs molécules d'acides nucléiques. La composition peut être utilisée sous la forme d'éléments hybridables d'un jeu ordonné de microéchantillons. La présente invention concerne aussi des procédés pour cribler des composés et des agents thérapeutiques à la recherche de réactions métaboliques indiquant la présence d'un composé toxique.

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