C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12Q 1/37 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2191895
A toxin assay that uses a substrate for cleavage by the toxin and antibodies that do not recognise the substrate but recognise and bind to the product of cleavage of the substrate by the toxin. The substrate can be a nerve cell peptide when the assay is for botulinum toxin or tetanus toxin.
Le dosage de toxines selon la présente invention fait intervenir un substrat destiné au clivage par la toxine et des anticorps ne reconnaissant pas le substrat, mais reconnaissant et établissant une liaison avec le produit obtenu après le clivage du substrat par la toxine. Le substrat peut être un peptide des cellules nerveuses lorsque le dosage porte sur la toxine botulinique ou la tétanique.
Hallis Bassam
James Benjamin Arthur Frederick
Quinn Conrad Padraig
Shone Clifford Charles
Goudreau Gage Dubuc
Microbiological Research Authority
Syntaxin Limited
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