Toxin conjugated eph receptor antibodies

Details Toxin conjugated eph receptor antibodies Toxin conjugated eph receptor antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61P 35/00 (2006.01) C12N 15/13 (2006.01)

Patent

CA 2621502

The present invention relates to compositions and methods for inducing cell death or stasis in cancer cells or other hyperproliferative cells using anti- EphA2 or anti-EphA4 antibodies conjugated to toxins.

L'invention concerne des compositions et des méthodes servant à induire une apoptose ou une stase dans des cellules cancéreuses ou d'autres cellules hyperprolifératives au moyen d'anticorps anti-EphA2 ou anti-EphA4 conjugués à des toxines.

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