Toxoplasma gondii antigens, p35, and uses thereof

Details Toxoplasma gondii antigens, p35, and uses thereof Toxoplasma gondii antigens, p35, and uses thereof

G - Physics

01

N

G01N 33/569 (2006.01) C07K 14/45 (2006.01) A61K 39/002 (2006.01) C12N 15/30 (2006.01)

Patent

CA 2333598

The present invention relates to combinations or mixtures of antigens which may be used in the detection of IgM and/or IgG antibodies to Toxoplasma gondii as well as to the P35 antigen which may be used to distinguish acute from chronic Toxoplasmosis. Furthermore, the present invention also relates to methods of using these combinations of antigens, antibodies raised against these combinations of antigens or against the novel P29 antigen thereof, as well as kits and vaccines containing the antigens present in the combinations.

Cette invention a trait à des combinaisons ou à des mélanges d'antigènes pouvant être utilisés aux fins de la détection d'anticorps IgM et/ou IgG contre Toxoplasma gondii ainsi qu'à l'antigène P35 pouvant être utilisé pour distinguer la toxoplasmose aiguë de la toxoplasmose chronique. Elle concerne, de surcroît, des méthodes d'utilisation des combinaisons d'antigènes, des anticorps dirigés contre ces combinaisons ou contre le nouvel antigène P29, ainsi que des nécessaires et des vaccins contenant les antigènes présents dans lesdites combinaisons.

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