Tr1 cells for use in atherosclerosis

A - Human Necessities – 61 – K

Patent

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Details

A61K 35/14 (2006.01) C12N 5/0783 (2010.01) A61P 9/10 (2006.01)

Patent

CA 2575689

The present invention relates to a method of treating or preventing atherosclerosis comprising administering to a mammal in need of such a treatment a) an antigen which has been used to activate in vitro a Tri cell population originating from said mammal, and b) the TO cell population activated by said antigen, said TO cell population being obtained from a CD4+ T lymphocyte population of said mammal.

L'invention concerne un procédé permettant de traiter ou de prévenir l'athérosclérose, qui consiste à administrer à un mammifère nécessitant un tel traitement: a) un antigène qui a servi à activer in vitro une population de cellules Tr1 originaire dudit mammifère, et b) la population de cellules Tr1 activée par ledit antigène, ladite population de cellules Tr1 étant obtenue à partir d'une population de lymphocytes CD4+ T dudit mammifère.

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